Pressure-driven flow through a single nanopore
نویسندگان
چکیده
منابع مشابه
Voltage-driven DNA translocations through a nanopore.
We measure current blockade and time distributions for single-stranded DNA polymers during voltage-driven translocations through a single alpha-hemolysin pore. We use these data to determine the velocity of the polymers in the pore. Our measurements imply that, while polymers longer than the pore are translocated at a constant speed, the velocity of shorter polymers increases with decreasing le...
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Discrete fluid volumes (plugs) are often needed for micro bioassay. Current methods of isolating discrete volumes use electrokinetic forces that require high voltages and result in ionic component separation of the sample. Pressure-driven flow through a double-T metering junction is a suggested alternative to this electrokinetic method. There has been no extensive analysis of pressure-driven pl...
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We investigate the translocation of a single stranded DNA (ssDNA) through a pore, which fluctuates between two conformations, by using coupled master equations (ME). The probability density function (PDF) of the first passage times (FPT) of the translocation process is calculated, displaying a triple, double or mono-peaked behavior, depending on the system parameters. An analytical expression f...
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Nanopore-based biosensing has attracted more and more interests in the past years, which is also regarded as an emerging field with major impact on bio-analysis and fundamental understanding of nanoscale interactions down to single-molecule level. In this work, the voltage-driven translocation properties of goat antibody to human immunoglobulin G (IgG) are investigated using nanopore arrays in ...
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ژورنال
عنوان ژورنال: Physical Review E
سال: 2012
ISSN: 1539-3755,1550-2376
DOI: 10.1103/physreve.86.025302